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Skin Temperature Monitoring Reduces the Risk for
Diabetic Foot Ulceration in High-risk Patients
David G. Armstrong, DPM, PhD, Katherine Holtz-Neiderer, DPM, Christopher Wendel, MS, M. Jane Mohler, PhD, Heather R. Kimbriel, Lawrence . Lavery, DPM, MPHd

In diabetes, as in other chronic diseases, self-care is an
essential element of disease management and prevention.
Most diabetic lower extremity complications involve sensory
neuropathy; patients do not recognize that their feet are
being injured until a wound develops ...

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FORA Publications, Our pipeline of R&D which emphasizes on the chronic diseases care, personal home care, point-of-care testing and telehealth applications which are main objectives that we want to find out the better solutions and design the more advanced products
Hypertension and Diabetes: Should We Treat Early Surrogates?
University Hospital, Malmö, Sweden

Type 2 diabetes, a major public health problem of great concern, affects millions of patients in both developed and developing countries. These patients run a well-documented increased risk of cardiovascular disease (CVD), the risk of which is two- to threefold greater than that seen in nondiabetic subjects ...

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FORA Publications, Our pipeline of R&D which emphasizes on the chronic diseases care, personal home care, point-of-care testing and telehealth applications which are main objectives that we want to find out the better solutions and design the more advanced products
The metabolic syndrome in hypertension: European society of hypertension position statement
Josep Redona, Renata Cifkovab, Stephane Laurentc, Peter Nilssond, Krzysztof Narkiewicze, Serap Erdinef and Giuseppe Manciag
- on behalf of the Scientific Council of the European Society of Hypertension

The metabolic syndrome considerably increases the risk of
cardiovascular and renal events in hypertension. It has been
associated with a wide range of classical and new
cardiovascular risk factors as well as with early signs of
subclinical cardiovascular and renal damage ...

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FORA Publications, Our pipeline of R&D which emphasizes on the chronic diseases care, personal home care, point-of-care testing and telehealth applications which are main objectives that we want to find out the better solutions and design the more advanced products
Cost-Effectiveness of Prevention and Treatment of the Diabetic Foot
MONICA MARIA ORTEGON, WILLIAM KEN REDEKOP, LOUIS WILHELMUS NIESSEN
- Netherlands Institute of Health Sciences, Erasmus University, Rotterdam
- Institute for Medical Technology Assessment, Erasmus University, Rotterdam

Diabetes is becoming one of the most common chronic diseases in the Netherlands. An age-related increase in the prevalence of diabetes of 32– 36% is estimated for the period from 1995 to 2010, at the end of which 400,000–500,000 cases are expected.

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FORA Publications, Our pipeline of R&D which emphasizes on the chronic diseases care, personal home care, point-of-care testing and telehealth applications which are main objectives that we want to find out the better solutions and design the more advanced products
The Economic Costs of Undiagnosed Diabetes
Yiduo Zhang, Ph.D.,Timothy M. Dall, M.S.,Sarah E. Mann, B.S.,Yaozhu Chen, M.P.A., Jaana Martin, B.A.,Victoria Moore, B.S.,Alan Baldwin, M.A.,Viviana A. Reidel, M.D., William W. Quick, M.D., F.A.C.P., F.A.C.E.
- The Lewin Group, Falls Church, Virginia
- Ingenix=i3 Pharmainformatics, Cary, North Carolina
- Ingenix=i3 Research, Basking Ridge, New Jersey

ne-fourth of the approximately 23.6 million people with diabetes in the United States are unaware they have the disease. While much is known about the population with diagnosed diabetes mellitus (DDM), data limitations have contributed to a paucity of information on the health care use patterns and economic burden associated with undiagnosed diabetes mellitus (UDM)— defined as unknowingly having an elevated glucose level that meets the definition of diabetes.

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Variability in Activity May Precede Diabetic Foot Ulceration
DAVID G. ARMSTRONG, CHRISTOPHER S. WENDEL, LAWRENCE A. LAVERY, BRENT P. NIXON, KATHERINE HOLTZ-NEIDERER, ANDREW J.M. BOULTON, MARTHA J. MOHLER
- Rosalind Franklin University of Medicine and Science, Chicago, Illinois
- Department of Surgery, Southern Arizona Veterans Affairs Medical Center,Tucson,
Arizona
- Department of Surgery, Texas A&M University, Temple, Texas
- 4Department of Medicine, Manchester Royal Infirmary, University of Manchester, U.K

Diabetic foot ulcers and related maladies continue to be among the most common serious diabetesrelated sequelae, affecting some 68 per 1,000 individuals with diabetes per annum in the U.S. The pathologic process leading to the vast majority of foot ulcerations is a consistent one. In the face of neuropathy, pressure multiplied by repetitive moderate stress leads to inflammation and subsequent autolysis of soft tissue overlying bony prominences

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FORA Publications, Our pipeline of R&D which emphasizes on the chronic diseases care, personal home care, point-of-care testing and telehealth applications which are main objectives that we want to find out the better solutions and design the more advanced products
Home Monitoring of Foot Skin Temperatures to Prevent Ulceration
LAWRENCE A. LAVERY, RUBEN G. ZAMORANO, KEVIN R. HIGGINS, DAVID G. ARMSTRONG, DAN R. LANCTOT, KYRIACOS A. ATHANASIOU, GEORGE P. CONSTANTINIDES, C. MAULI AGRAWAL
- College of Medicine, TexasA&MHealth Science Center, Scott and White
Hospital, Temple, Texas
- Xilas Medical, San Antonio, Texas
- Dr. William M. Scholl College of Podiatric Medicine, Rosalind Franklin University
of Medicine, Chicago, Illinois
- Department of Bioengineering, Rice University, Houston, Texas
- Department of Biomedical Engineering, The University of Texas, San Antonio,
Texas

Foot ulcers are one of the most common precursors to diabetes-related amputations. Other factors that have been associated with amputation, such as infection, faulty wound healing, and ischemia, usually do not cause tissue loss or amputation in the absence of a wound. Therefore, ulcer prevention is one of the foci of any amputation prevention program.

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Hypertension in people with Type 2 diabetes

The International Diabetes Federation (Europe) has updated these guidelines on hypertension management specifically in Type 2 diabetes in the light of recent results of the first prospective, randomized controlled studies to investigate clinical outcomes in people with diabetes and hypertension. The guidelines are knowledge based, i.e. based not only on evidence originating from clinical trials, but also from epidemiological and pathophysiological studies. A successful management strategy requires the following components: 1. Regular surveillance to detect developing hypertension and other cardiovascular (CV) risk factors...

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